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Mishel Theory in Illness

Paper will be submitted through Turnitin.

Using Mishel’s Uncertainty in Illness Theory Paper (This paper was divided; this are the 2 questions I need to answer)

1- Demonstrate how the theory has been used in areas of nursing practice- Provide varied examples (peer -reviewed journal articles). (These articles are examples that can be used)

Chen, T. Y., Kao, C. W., Cheng, S. M., & Chang, Y. C. (2018). Uncertainty and depressive symptoms as mediators of quality of life in patients with heart failure. PloS one, 13(11), e0205953. https://doi.org/10.1371/journal.pone.0205953

Delis P. C. (2019). Uncertainty and Quality of Life in Systemic Lupus Erythematosus: A Cross-sectional Study. Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses, 44(1), 2–10. https://doi.org/10.1097/rnj.0000000000000118

Guan, T., Santacroce, S. J., Chen, D. G., & Song, L. (2020). Illness uncertainty, coping, and quality of life among patients with prostate cancer. Psycho-oncology, 29(6), 1019–1025. https://doi.org/10.1002/pon.5372

Lebel, S., Maheu, C., Tomei, C., Bernstein, L. J., Courbasson, C., Ferguson, S., Harris, C., Jolicoeur, L., Lefebvre, M., Muraca, L., Ramanakumar, A. V., Singh, M., Parrott, J., & Figueiredo, D. (2018). Towards the validation of a new, blended theoretical model of fear of cancer recurrence. Psycho-oncology, 27(11), 2594–2601. https://doi.org/10.1002/pon.4880

Zhang Y. (2017). Uncertainty in Illness: Theory Review, Application, and Extension. Oncology nursing forum, 44(6), 645–649.

2- Application -Propose one new/novel use of the theory in a specific area of nursing practice. Explain the “theory in action.” Describe the application of the theory.

Novel way of using the theory (this new application was approved by the professor, needs to be used) Using Mishel’s Uncertainty in Illness Theory un patients 65 years of age and older with a diagnosis of Glaucoma. 

(This are some articles I found that can be used)

Glaucoma and cataract are the two leading causes of blindness worldwide. It is estimated that there will be 11.2 million cases of blindness worldwide due to glaucoma, Zhang et al., 2018.  

The loss of vision is not only associated with physical suffering, but also with mental distress, including illness uncertainty and psycho-logical disorders.  

Mental distress has always been neglected by doctors and nurses, which can negatively affect therapy and quality of life, Jampel et al., 2007.  

Once patients are diagnosed with glaucoma or cataract, the lack of communication and information stimulates the process of uncertainty, which includes unfamiliarity, ambiguity, vagueness, doubt and unpredictability, Mishel, (1981).  


Mishel M. H. (1988). Uncertainty in illness. Image–the journal of nursing scholarship, 20(4), 225–232.

Zhang, D., Fan, Z., Gao, X., Huang, W., Yang, Q., Li, Z., Lin, M., Xiao, H., & Ge, J. (2018). Illness uncertainty, anxiety and depression in Chinese patients with glaucoma or cataract. Scientific Reports, 8(1), 11671.

Mishel, M. H. The measurement of uncertainty in illness. Nurs Res 30, 258–63 (1981). 

Jampel, H. D. et al. Depression and mood indicators in newly diagnosed glaucoma patients. Am J Ophthalmol 144, 238–244 (2007).